| 8 a.m.-12:30 p.m. |
Morning Session: Overview, Interaction with Other Programs |
| 7:45 a.m.-5 p.m. |
Registration
|
| 8-8:20 a.m. |
Continental Breakfast |
| 8:20-8:30 a.m. |
Welcome, Introductions, Announcements |
| 8:30-8:45 a.m. |
Opening Remarks
Barbara M. Alving, M.D., Acting Director, National
Center for Research Resources (NCRR) |
| 8:45-9 a.m. |
Program Introduction
Douglas Sheeley, NCRR
|
| 9-9:25 a.m. |
New Tools for Exploring the Dynamic Interactome
Michael P. Rout, Rockefeller University |
| 9:25-9:50 a.m. |
Center on Proteolytic Pathways
Jeffrey W. Smith, Burnham Institute |
| 9:50-10:15 a.m. |
Fluorescent Probes and Imaging for Networks and Pathways
Alan S. Waggoner, Carnegie Mellon University |
| 10:15-10:30 a.m. |
Break |
| 10:30-10:55 a.m. |
Technology Center on Networks and Pathways of Lysine Modification
Jef D. Boeke, Johns Hopkins University |
| 10:55-11:20 a.m. |
Polarity in Networks and Pathways
Ann Cowan, University of Connecticut School of Medicine and Dentistry |
| 11:20a.m.-12:30 p.m. |
Overviews of Related National Institutes of Health (NIH) Programs and Panel Discussion
The NIH Roadmap for Structural Biology
John Norvell and Jean Chin, National Institute of General Medical Sciences (NIGMS)
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Probe Production from NIH's Molecular Libraries Initiative 
Carson Loomis, National Human Geonome Research Institute (NHGRI)
|
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Exploratory Centers for Development of High Resolution Probes for Cellular Imaging
Richard Rodewald, NIGMS |
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The National Heart, Lung, and Blood Institute (NHLBI) Proteomics Consortium 
Susan Old, NHLBI
|
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NIH National Centers for Biomedical Computing: Building Collaborations
Jennifer Larkin, NHLBI |
| 12:30-1:30 p.m. |
Lunch (on your own)
|
| 1:30-5 p.m. |
Afternoon Session: Imaging and Probes
|
| 1:30-2:05 p.m. |
Protease Activity Imaging Technology
Jeffrey W. Smith, Burnham Institute |
| 2:05-2:40 p.m. |
New Probes for Networks and Pathways
Peter Berget, Carnegie Mellon University |
| 2:40-3:15 p.m. |
Probing Networks and Pathways with Holographic Optical Tweezers
Eric Dufresne, Yale University |
| 3:15-3:45 p.m. |
Break
|
| 3:45-4:20 p.m. |
Recent Advances in Proteomics Integrated with Fluorescence Imaging
Ileana Cristea, Rockefeller University |
| 4:20-5 p.m. |
Advances in Imaging Instrumentation and Applications
Simon Watkins, University of Pittsburgh and Marcel Bruchez, Carnegie Mellon University |
| 5:00-7:30 p.m. |
Dinner (on your own)
|
| 5:00-7:30 p.m. |
Dinner meeting of NTCNP Steering Committee (Marriott)
|
| 7:30-9:30 pm |
Poster Session, Bethesda Marriott at Pooks Hill All are welcome
|
| 8 a.m.-12:30 p.m. |
Morning Session: Modeling, Computation, and Informatics |
| 7:45 a.m.-3:30 p.m. |
Registration
|
| 8-8:20 a.m. |
Continental Breakfas
|
| 8:20-8:30 a.m. |
Announcements
|
| 8:30-9:05 a.m. |
Image Informatics Tools in Support of Systems Modeling
Robert Murphy, Carnegie Mellon University |
| 9:05-9:40 a.m |
The Virtual Cell 
James Schaff, University of Connecticut Health Center |
| 9:40-10:15 a.m. |
Mapping Pathways from the Outside in
Joel Bader, Johns Hopkins Medical Institutions |
| 10:15-10:30 a.m. |
Break
|
| 10:30-11:05 a.m. |
P-MAP: The Proteolysis Map
Adam Godzik, Burnham Institute |
| 11:05-11:40 a.m. |
Modeling of Macromolecular Assemblies by Satisfaction of Spatial Restraints
Frank Alber, University of California, San Francisco |
| 11:40 a.m.-12:15 p.m. |
Tools for Collaboration: Primers on the NTCNP Wiki and VDC
Ion Moraru, University of Connecticut Health Center |
|
Nanomedicine Development Centers an Overview for the TCNP Grantees
David Balshaw, National Institute of Environmental Health Sciences |
| 12:15-1:15 p.m. |
Lunch (on your own)
|
| 1:15-3:35 p.m. |
Afternoon Session: High-throughput Technologies
|
| 1:15-1:50 p.m. |
High-throughput Microarray Analysis
John Aitchison, Institute for Systems Biology |
| 1:50-2:25 p.m. |
Detection of Proteolytic Signatures by Mass Spectrometry
Mari Enoksson, Burnham Institute |
| 2:25-2:55 p.m. |
Unraveling Lysine Modifications Using a Protein Chip Approach
Heng Zhu, Johns Hopkins Medical Institutions |
| 2:55-3:05 p.m. |
Tandem Time-of-Flight MassSpectrometry Analysis of Lysine Modifications
Robert J. Cotter, Johns Hopkins Medical Institutes |
| 3:05-3:35 p.m. |
High-throughput Technologies and Resources for Studies of Lysine Modification
Jef Boeke, Johns Hopkins Medical Institutions |
| 3:35 p.m. |
Meeting Adjourn
|